CME Current Therapy of Cutaneous Melanoma
نویسنده
چکیده
Learning Objectives: After studying this article, the participant should be able to: 1. Cite histopathologic and patientrelated risk factors associated with an increased risk of melanoma recurrence. 2. Describe the appropriate margin(s) of surgical excision for primary cutaneous melanoma. 3. Discuss the controversies and review current options for management of regional lymph nodes. 4. Describe the current status of adjuvant therapy for melanoma.
منابع مشابه
Current Research and Development of Chemotherapeutic Agents for Melanoma
Cutaneous malignant melanoma is the most lethal form of skin cancer and an increasingly common disease worldwide. It remains one of the most treatment-refractory malignancies. The current treatment options for patients with metastatic melanoma are limited and in most cases non-curative. This review focuses on conventional chemotherapeutic drugs for melanoma treatment, by a single or combination...
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Cutaneous melanoma is one of the most aggressive forms of skin cancer, and is correlated with a large proportion of skin cancer-related deaths. Therapy for cutaneous melanoma has advanced greatly through careful identification of therapeutic targets and the development of novel immunotherapeutic approaches. The identification of BRAF as well as other driver mutations, have allowed for a special...
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Ocular melanoma is the second most common type of melanoma after cutaneous and the most common primary intraocular malignant tumor in adults. Large majority of ocular melanomas originate from uvea, while conjunctival melanomas are far less frequent. Incidence of uveal melanoma has remained stable over last three decades. Diagnosis is in most cases established by clinical examination with great ...
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Background: P53 tumor suppressor gene mutation is one of the most common genetic alterations in human malignancies. The mutated from of the gene is stable and can be detected with immunohistochemistry methods. There is much controversy about the expression rate of this gene in malignant melanoma. Objective: To determine the frequency of the P53 antigen expression by sex, age, type and thickness...
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